Frequently Asked Questions

Everything researchers commonly ask us, answered in one place.

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🛡 Are all products independently tested?

Yes. Every batch is verified through independent Janoshik HPLC analysis.

Each MOTS-c batch supplied is tested by Janoshik Analytical, an independent peptide-analysis laboratory based in the Czech Republic. Reported purity consistently exceeds 99%.

Where a current batch report is available, a printed Certificate of Analysis (COA) is included with the order. Otherwise, verification details are published through our Purity page.

Every COA includes a unique verification code that can be checked against Janoshik’s own records, allowing researchers to independently confirm authenticity and testing results.

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💧 Reconstitution Guide

Mixing BAC water with lyophilised powder

Four simple steps:

1. Clean the vial
Wipe the vial stopper with an alcohol prep wipe and allow it to dry.

2. Draw BAC water
Using an insulin syringe, draw 2 mL of bacteriostatic water.

3. Add slowly
Inject the BAC water gently down the inside wall of the vial. Avoid applying the solution directly onto the powder.

4. Dissolve carefully
Swirl gently until fully dissolved. Do not shake. Allow approximately 30 seconds, then refrigerate.

Use the included reconstitution guide inside the packaging for future reference.

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💉 Pen Guide

Dial settings, priming and preparation

Attach a fresh needle
Clean the pen tip with an alcohol wipe and attach a new sterile needle.

Prime the pen
Turn the dial one click, point the needle upward, and press the dose button. A small droplet at the needle tip confirms successful priming and removal of air.

Set the research amount
Each dial click represents a fixed increment based on the pen calibration. The display shows the selected amount.

Example: a 6 mg research setting may require approximately 6–12 clicks depending on calibration.

Use the route described in published research
Published research protocols describe subcutaneous administration sites including the abdomen, thigh, and upper arm.

After use

• Dispose of the needle safely.
• Replace the pen cap.
• Return the pen to refrigerated storage.

Each pen provides the number of uses shown in the relevant protocol information. When empty, replace the cartridge while continuing to use the same pen body.

Research use only. This information summarises published research procedures and is not medical or human-use guidance.

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❄ Storage Information

Lyophilised MOTS-c

• Store sealed at 2–8°C
• Protect from light
• Do not freeze
• Stable for extended refrigerated storage

Reconstituted Solution

• Store at 2–8°C
• Keep in the original vial
• Avoid shaking
• Discard if cloudy or visibly changed

BAC Water

• Refrigerate after opening
• Use within approximately 30 days

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📍 Administration Information

Route described in published studies

Published MOTS-c research describes subcutaneous administration routes, including sites such as the abdomen, thigh, and upper arm.

Research protocols commonly rotate administration locations to minimise repeated local stress.

This information is provided only as scientific background from published literature. We do not provide human-use instructions, dosing recommendations, or medical guidance.

Reference: Lee et al. 2015

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🎯 Research Protocol Information

What amount should researchers use?

Published MOTS-c research commonly evaluates gradual progression through study phases, beginning with lower research stages before moving to later stages.

Researchers should follow the relevant protocol framework for their study design.

For researchers new to this compound, published approaches typically begin with an initial research phase before progressing.

Researchers already familiar with MOTS-c can review the available protocol stages to determine the appropriate research requirements.

For custom laboratory schedules, contact our team before ordering so we can help identify the most suitable vial size and format.

Research use only. Information is based on peer-reviewed literature and does not constitute medical guidance.

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Key Information

Property	Details
Compound	MOTS-c
Research Category	Longevity Research
Available Sizes	10 mg, 15 mg, 20 mg, 30 mg, 40 mg
Price	From £55
Format	Lyophilised powder in sealed vial
Purity	>99% HPLC verified by Janoshik Analytical
Intended Use	In-vitro laboratory research only

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Chemical & Reference Data

Information compiled from public databases and peer-reviewed literature for laboratory characterisation.

Property	Details
Compound Class	Synthetic 16-amino-acid mitochondrial-derived peptide
Molecular Formula	C₁₀₀H₁₆₇N₂₇O₂₂S
Molecular Weight	2174.6 g/mol
CAS Number	1627580-64-6
Amino Acid Count	16
Sequence	MRWQEMGYIFYPRKLR
Research Mechanism	Mitochondrial-derived peptide studied in AMPK signalling pathways
Reported Half-life	Short serum half-life reported in preclinical literature
Solubility	Reconstitutes in bacteriostatic water for laboratory use
Lyophilised Storage	Refrigerated storage recommended
Reconstituted Storage	Refrigerated storage recommended
Regulatory Status	Preclinical / investigational

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Research Profile

• Mitochondrial-derived peptide
• 16-amino-acid sequence
• Studied in AMPK and metabolic signalling models
• Third-party purity tested
• Research use only

MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within mitochondrial DNA. Scientific literature characterises MOTS-c as a peptide studied in cellular and preclinical models involving AMPK signalling and metabolic pathways.

The product is supplied as a lyophilised powder intended exclusively for laboratory research.

Descriptions above reflect published scientific characterisation and do not represent claims regarding effects in humans.

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Laboratory Handling

MOTS-c is supplied as a freeze-dried powder in a sealed glass vial.

For laboratory preparation:

• Add the required diluent slowly along the inside wall of the vial.
• Swirl gently until dissolved.
• Avoid shaking or vortexing.
• Store prepared solutions at 2–8°C.

A reconstitution calculator can be used to determine final concentration.

State	Temperature	Typical Stability
Lyophilised	2–8°C or -20°C	Up to 24 months
Reconstituted	2–8°C	Approximately 4–6 weeks

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Purity & Verification

Every MOTS-c batch undergoes independent HPLC verification by Janoshik Analytical.

Where available, the batch Certificate of Analysis includes a unique verification key that can be authenticated against Janoshik records.

Reported purity consistently exceeds 99%.

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Related Research Compounds

Researchers studying MOTS-c may also explore:

• NAD+ – Longevity Research
• Epithalon – Longevity Research
• AICAR – Metabolic Research

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Literature Reference

Lee C. et al.
The mitochondrial-derived peptide MOTS-c.
Cell Metabolism (2015). PMID: 25738459

References are independent peer-reviewed publications. Vantix Bio is not affiliated with these studies or their authors.