Frequently Asked Questions

Answers to the questions researchers contact us about most often, all in one place.

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🛡 Are products independently tested?

Janoshik HPLC verification on every batch

Yes. Every batch is independently verified using HPLC analysis.

All PT-141 (Bremelanotide) supplied is tested by Janoshik Analytical, an independent peptide-analysis laboratory based in the Czech Republic. Reported purity results consistently exceed 99%.

Where a current batch report is available, a printed Certificate of Analysis (COA) is supplied with the order. If a report is not included, batch verification details are published through our Purity page.

Every COA contains a unique verification key that can be validated through Janoshik’s own portal, allowing researchers to independently confirm testing information.

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💧 Reconstitution Guide

Preparing BAC water with lyophilised powder

Four preparation steps:

1. Clean the vial stopper
Use an alcohol prep wipe to clean the vial top and allow it to dry.

2. Draw bacteriostatic water
Using an insulin syringe, draw 2 mL of BAC water.

3. Add slowly to the vial
Inject the solution carefully down the inside wall of the vial. Avoid directing liquid directly onto the powder.

4. Dissolve gently
Swirl carefully until completely dissolved. Do not shake. Allow approximately 30 seconds before refrigerating.

Use the included reconstitution guide inside the packaging for future reference.

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💉 Pen Guide

Dose dial, priming and preparation

Preparing the pen

Attach a fresh needle
Clean the pen tip using an alcohol wipe and attach a new sterile needle.

Prime the pen
Dial one click, hold the pen with the needle facing upward, and press the dose button. A small droplet at the needle tip confirms successful priming and removal of air.

Set the research amount
Each dial click represents a fixed increment according to pen calibration. The display indicates the selected amount.

Example: a 6 mg research setting may correspond to approximately 6–12 clicks depending on calibration.

Follow routes described in published research
Published research protocols describe subcutaneous administration sites including the abdomen, thigh, and upper arm.

After use

• Dispose of the needle safely in a sharps container.
• Replace the pen cap.
• Return the pen to refrigerated storage.

Each pen provides the number of uses listed for the selected size. When empty, replace the cartridge while continuing to use the same pen body.

Research use only. Procedures are described from published research protocols and do not constitute medical or human-use guidance.

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❄ Storage Information

Lyophilised PT-141

• Store sealed at 2–8°C
• Protect from light
• Do not freeze
• Stable for 24+ months under recommended conditions

Reconstituted Solution

• Store at 2–8°C
• Keep in the original glass vial
• Do not shake
• Discard if cloudy or discoloured

BAC Water

• Refrigerate after opening
• Use within approximately 30 days

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📍 Administration Information

Route described in published studies

Published PT-141 (Bremelanotide) research describes subcutaneous administration routes, including sites such as the abdomen, thigh, and upper arm in pharmacokinetic and clinical research settings.

Research protocols commonly rotate administration locations to minimise repeated local tissue stress.

This information is provided solely as scientific context from peer-reviewed literature. We do not provide medical advice, human-use guidance, or administration protocols.

Reference: Diamond et al. 2004

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🎯 Research Protocol Information

What amount should researchers use?

Published PT-141 (Bremelanotide) research commonly evaluates structured protocols involving gradual progression through research phases.

Researchers should follow the appropriate protocol framework for their study design.

New researchers

Those beginning work with PT-141 typically review initial research phases before progressing through later study stages.

Experienced researchers

Researchers familiar with the compound can review protocol information to determine suitable research requirements and compare available formats.

Custom research schedules

For non-standard laboratory protocols, contact our team before ordering. We can help identify the most suitable product format based on your planned research requirements.

Research use only. Information is derived from peer-reviewed literature and does not represent medical guidance.

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Key Information

Specification	Details
Compound	PT-141 (Bremelanotide)
Research Category	Melanocortin Research
Available Size	10 mg
Pricing	From £45
Format	Lyophilised powder in sealed vial
Purity	>99% HPLC verified by Janoshik Analytical
Intended Use	In-vitro laboratory research only

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Chemical & Reference Data

Information compiled from public databases and peer-reviewed literature for research and laboratory characterisation.

Property	Details
Compound Class	Synthetic 7-amino-acid α-MSH analogue
Molecular Formula	C₅₀H₆₈N₁₄O₁₀
Molecular Weight	1025.18 g/mol
CAS Number	189691-06-3
PubChem CID	9941379
Residue Count	7 amino acids
Sequence	Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Research Mechanism	Melanocortin receptor agonist profile, including MC4R activity
Reported Half-life	Approximately 2.7 hours in human serum
Solubility	Reconstitutes in bacteriostatic water for laboratory use
Lyophilised Storage	2–8°C recommended
Reconstituted Storage	2–8°C recommended
Regulatory Status	Approved as Vyleesi for specific indications

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Research Profile

• Cyclic heptapeptide α-MSH analogue
• Melanocortin receptor agonist
• MC4R activity profile studied in literature
• Independently purity tested
• Research use only

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analogue of α-MSH. Scientific literature characterises it as a compound studied for activity at melanocortin receptors, including MC4R-related pathways.

It is supplied as a lyophilised powder intended exclusively for laboratory research.

The information above describes published scientific characterisation and does not represent claims regarding effects in humans.

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Laboratory Handling

PT-141 (Bremelanotide) is supplied as a freeze-dried powder in a sealed glass vial.

For laboratory preparation:

• Add the required diluent slowly down the vial wall.
• Swirl gently until dissolved.
• Do not vortex or shake.
• Store prepared solutions at 2–8°C.

A reconstitution calculator can be used to determine the final concentration (mg/mL).

State	Temperature	Typical Stability
Lyophilised	2–8°C or -20°C	Up to 24 months
Reconstituted	2–8°C	Approximately 4–6 weeks

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Purity & Verification

Every PT-141 (Bremelanotide) batch undergoes independent HPLC verification by Janoshik Analytical.

Where available, the batch Certificate of Analysis includes a unique verification key that can be authenticated against Janoshik records.

Reported purity consistently exceeds 99%.

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Related Research Compounds

Researchers studying PT-141 may also explore:

• MT-1 (Afamelanotide) – Melanocortin Research
• Melanotan II (MT-2) – Melanocortin Research
• Kisspeptin-10 – Neuropeptide Research